Sensitive digital quantification of DNA methylation in clinical samples
نویسندگان
چکیده
منابع مشابه
A methylation sensitive dot blot assay (MS-DBA) for the quantitative analysis of DNA methylation in clinical samples.
BACKGROUND There is increasing interest in DNA methylation and in its implication in transcriptional gene silencing, a phenomenon commonly seen in human cancer. AIMS To develop a new method that would allow quantitative DNA methylation analysis in a large range of clinical samples, independently of the processing protocol. METHODS A methylation sensitive dot blot assay (MS-DBA) was develope...
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ژورنال
عنوان ژورنال: Nature Biotechnology
سال: 2009
ISSN: 1087-0156,1546-1696
DOI: 10.1038/nbt.1559